From: Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
Outcome | Type of measure | Rater | Reliability | Responsiveness | MCID | Used in DLB trials |
---|---|---|---|---|---|---|
ADCS-ADL | ADLs | Informant |  +  |  +  | 2 points | |
DAD | ADLs | Informant |  +  |  +  | NE | |
UPDRS-II | ADLs | Informant Subject | NE | NE | NE | |
SEADL | ADLS | Informant | NE | NE | NE | No |
QOL-AD | QoL | Subject |  +  |  +  | NE | Yes [32] |
PDQ-39 | QoL | Subject | +/− | NE | NE | No |
ZBI | CB | Informant | +/− |  +  | 13 points | |
RSS | CB | Informant |  +  | NE | NE | No |
CIBIC+ | IoC | Clinician/Informant | +/− |  +  | NE | |
CGI | IoC | Clinician | +/− |  +  | NE | |
ADCS-CGIC | IoC | Clinician | +/− |  +  | 1 point |