Table 2 Types of outcome measures
From: Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
Outcome measure | Example | Advantage | Disadvantage |
|---|---|---|---|
Direct/objective | Falls/death | Easy to measure | May not capture the symptom severity or impact on daily life |
Performance outcome | Neuropsychological evaluation | Objective measure | Only evaluating one point in time—not a reflection of the current status |
Artificial environment | |||
Clinician reported outcome | Clinical scales | Clinical relevance | Depends on expertise of administrator |
Patient-reported outcome | Quality of life questionnaires | Centered on the patient | Impaired cognition may affect reliability of responses |
Observer-reported outcome | Activities of daily living questionnaires | Provides a better assessment of daily function | Subject to bias or caregiver’s cognitive ability |