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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Clinical and genetic characterization of a large cohort of patients with Wilson’s disease in China

Fig. 3

Associations of sex (male), age-at-onset, and ATP7B variants with WD manifestations. a Binary logistic regression analysis of factors associated with neurologic presentation in hepatic and neurologic presentation patients (n = 941). b Binary logistic regression analysis of factors associated with acute hepatic WD in hepatic presentation patients (n = 276). c Binary logistic regression analysis of factors associated with dystonia, gait abnormality, swallowing difficulty, dysarthria, tremor, or salivation in neurologic presentation patients (n = 665). Only factors with significant associations in univariate analyses were included in the multivariate analysis. The P-values were adjusted with the Benjamini–Hochberg method. Cont., continuous variable, PTV, protein-truncating variants (e.g., frameshift, nonsense, splice sites)

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