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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia

Fig. 3

Correlation of pGFAP with plasma and CSF neurofilament light chain (a, b), CSF YLK-40 (c), and baseline MMSE score (d) in FTD, AD and cognitively normal participants. Correlation of pGFAP with baseline FTD-FRS score (e) and cortical thickness in FTD (f, n = 29). Blue regions in f represent a direct correlation. For illustrative purposes, a scatterplot shows the individual log(pGFAP) and the value of cortical thickness in the corresponding cortical region (marked with an asterisk) (f). P-value 10−1.3 = 0.05. All correlation analyses were adjusted by age and sex. pGFAP, plasma glial fibrillary acidic protein; pNfL, plasma neurofilament light chain; CN, cognitively normal participants; FTD, frontotemporal dementia; AD, Alzheimer’s disease

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