Fig. 4

Quantification of Aβ plaques and microglia and morphological analysis of microglia. a Representative images of microglia and Aβ plaque in PIL (Scale bar, 100 μm). b Estimated number of Aβ plaques per unit area in PIL and HPC (P = 0.051 by two-sample t-test) analyzed by unbiased stereology. c Estimated number of microglia per unit area in PIL and HPC analyzed by unbiased stereology. d Average length of microglial processes per cell in PIL and HPC. e Average number of microglia process endpoints per cell in PIL and HPC. *P < 0.05, one-way ANOVA with Tukey post-hoc test, n = 3