Fig. 4From: Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer’s disease: a proof-of-concept studyMean annual changes in the 18F-Florbetaben uptake after treatment. The mean annual changes in the 18F-Florbetaben SUVR of five participants after treatment. The colors illustrate the average value of absolute annual differences for the 18F-Florbetaben SUVR between pre and post-treatment. SUVR, Standardized uptake value ratioBack to article page