Skip to main content

Table 3 Cox regression analysis of interaction between PRS and APOE ε4 carrier status in association with disease progression from MCI to AD

From: Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment

 

Coefficient

Standard error

P-value

Age

0.034

0.009

1.94 × 10–4

Female

0.116

0.127

3.57 × 10–1

PRS+APOE

0.531

0.162

1.10 × 10–3

APOE ε4 carrier status

0.681

0.176

1.14 × 10–4

PRS+APOE × APOE ε4 carrier status

− 0.372

0.179

3.78 × 10–2

  1. PRS+APOE: PRS including SNPs within the 1 Mb-region surrounding the APOE gene
Back to article page

Translational Neurodegeneration

ISSN: 2047-9158

Contact us