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Fig. 9 | Translational Neurodegeneration

Fig. 9

From: Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Fig. 9

Sandwich ELISA displaying the binding curves of the different antibodies to α-synuclein aggregates. a Schematic representation of sandwich ELISA setup where the antigen (α-synuclein)  was captured by an antibody coated on the well surface. This is followed by the addition of the generated recombinant antibodies. b Hexa-RmAb158, Tetra-RmAb158 and RmAb158 displayed no binding to α-synuclein aggregates. The control antibody SynO2 displayed a strong binding to α-synuclein aggregates. Data are presented as mean ± SD, n = 3

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Translational Neurodegeneration

ISSN: 2047-9158

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