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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Fig. 1

Design of the different recombinant antibodies. a Schematic picture of RmAb158 antibody. b DVD-RmAb158, where the heavy and light chain variable domains are added to the N-terminal end of Rmab158 heavy and light chains, respectively. c Tetra-RmAb158, where scFvs are added to the N-terminal end of Rmab158 heavy chain only. d Hexa-RmAb158, where scFvs are added to the N-terminal end of the heavy and light chains of RmAb158. e SDS-PAGE showing a band approximately at 150 kDa for RmAb158, 200 kDa for both DVD-RmAb158 and Tetra-RmAb158, and around 250 kDa for Hexa-RmAb158

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Translational Neurodegeneration

ISSN: 2047-9158

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