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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials

Fig. 3

Scatter plot of disease progression rates (defined as ALSFRS-R slopes) and NfL blood levels at diagnosis. The NfL model formulas and corresponding regression lines derived from the multivariate regression in the development cohort are shown separately for patients with spinal (red) and bulbar onset (blue), to visualize the correlation between ALSFRS-R slopes and ln(NfL) levels and the interaction between ln(NfL) levels and site of onset

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