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Table 5 List of the aspects of AD pathology in which mechanical-based modality produced positive effects for each of the reviewed studies

From: Multi-mechanical waves against Alzheimer’s disease pathology: a systematic review

 

Aβ and/or Tau pathologies

Immunological response

Neurotoxicity and neuroplasticity deficits

Brainwave entrainment and brain functional connectivity

Behavioral performance

Cognitive and mood status

Motor ability

Whole-body vibration

Kawanable et al. [75]

     

X

Cheung et al. [74]

     

X

Furness and Maschette [73]

     

X

Cardinale et al. [100]

     

X

Machado et al. [77]

     

X

Marín et al. [79]

     

X

Beaudart et al. [102]

      

Zhang et al. [76]

     

X

Sievänen et al. [81]

      

Álvarez-Barbosa et al. [78]

     

X

Lam et al. [21]

     

X

Kim and Lee [67]

   

X

X

 

Zhu et al. [72]

     

X

Heesterbeek et al. [84]

      

Transcranial ultrasound stimulation

Jordão et al. [59]

X

X

    

Burgess et al. [38]

X

 

X

 

X

 

Leinenga and Götz [36]

X

X

  

X

 

O’Reilly et al. [62]

      

Leinenga and Götz [60]

X

X

    

Eguchi et al. [57]

X

X

X

 

X

 

Poon et al. [37]

X

     

Pandit et al. [66]

X

X

X

 

X

 

Karakatsani et al. [45]

X

X

X

   

Bobola et al. [61]

X

X

 

X

  

Shen et al. [58]

X

X

X

 

X

 

Lee et al. [56]

X

X

X

 

X

 

Lipsman et al. [63]

    

X

 

Meng et al. [68]

   

X

  

Beisteiner et al. [69]

   

X

X

 

Rezai et al. [82]

      

D’Haese et al. [65]

X

     

Auditory stimulation

Lee et al. [48]

X

X

 

X

  

Martorell et al. [30]

X

X

 

X

X

 

Clements-Cortes et al. [83]

    

X

 

Calomeni et al. [49]

   

X

X

 

Papalambros et al. [70]

   

X

X

 

Papalambros et al. [31]

   

X

X