Fig. 4
From: Optimization of cerebral organoids: a more qualified model for Alzheimer’s disease research
Applications of AD cerebral organoids. Qualified AD cerebral organoids may contain a variety of neuronal cells, a blood-brain barrier, and connections with other areas. These features can be used to test the blood-brain barrier permeabilities of drugs and compare them to the human brain permeabilities, to explore cerebral electrophysiology and connections between the brain and other organs, to study human diseases in the central nervous system (not just AD), and for epidemiological investigations