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Table 1 Demographic and clinical profiles of control and PD patients

From: Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease

Clinical parameters

Healthy controls

Stage II

Stage III

Stage IV

P value

Number of subjects

31

8

42

22

N/A

Age (years, mean ± SD)

63.94 ± 7.45

59.75 ± 7.55

61.62 ± 7.6

64.73 ± 8.14

0.2383

Age of onset (years, mean ± SD)

N/A

55 ± 7.53

53.6 ± 8.27

55.05 ± 10.89

0.6725

Sex (M/F)

17/14

5/3

26/16

12/10

0.0381

MMSE

N/A

26.63 ± 2.45

25.36 ± 2.32

24.18 ± 2.55

0.0392

UPDRS III

N/A

19.75 ± 2.90

25.1 ± 2.78

29.59 ± 4.45

< 0.0001

  1. M male, F female, MMSE Mini-Mental State Examination, UPDRS III Unified Parkinson’s Disease Rating Scale part III, N/A not applicable