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Table 5 Intervention protocols and results in the study that targeted the cerebellum

From: The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease: a systematic review

Study

Polarity of target electrode

Electrode size (cm2)

Intensity (mA)

Current density (mA/cm2)

Current density (mA/cm2)

Duration (min)

Number of sessions

Anatomical target (electrode placement)

Target electrode placement

Return electrode placement

State of medication during intervention

Combined intervention

Online/offline tDCS

Adverse effects

Outcome measurements

Timepoints of assessment

State of medication during assessment

Results

Conclusion

Effect size (typr)

Workman et al. 2020 [49]

Anode

T = R = 5 × 7

2 and 4

0.06 and 0.11

0.06 and 0.11

20

1

Cerebellum (medial edge 1 cm below and 2 cm lateral to the inion over the cerebellar hemisphere contralateral to the more PD-affected side)

Medial edge 1 cm below and 2 cm lateral to the inion over the cerebellar hemisphere contralateral to the more PD-affected side

Upper arm or medial edge 1 cm below and 2 cm lateral to the inion over the cerebellar hemisphere ipsilateral to the more PD-affected side

NR

Offline

Burning sensation, itching, tingling, pins/needles

25 ft. walk test; TUG; 6-min walk test, Berg Balance Scale

Before, after

NR

No significant effects on gait parameters but improvement in Berg Balance Scale

NR

  1. T target electrode; R reference electrode; NR not reported; →, no effect; TUG timed up and go; tDCS transcranial direct current stimulation