Fig. 1

Generation of three strains under different conditions and schematic illustration of the experimental timeline. a Negatively stained TEM images of the fibril assemblies generated in different conditions. Scale bar, 1 μm. Buffer A: 50 mM Tris, 150 mM KCl, pH 7.5; buffer B: 10 mM Tris, 50 mM NaCl pH 7.6; buffer C:10 mM MEZ, pH 5.5. b Schematic of the timeline of the study