Fig. 6From: Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patientsHypothalamic atrophy in ALS patients. a Representative T1w MRI of hypothalami of a healthy control and an ALS patient; hypothalami are shadowed in red (arrows). b The hypothalamic volume was significantly decreased in ALS patients (n = 72) compared to the controls (n = 43). Bars represent mean ± SD. ****P < 0.000 1Back to article page