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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

Fig. 2

Histological analysis of tyrosine hydroxylase (TH) in 6-OHDA rats with or without DP treatment. a TH immunoreactivity was decreased in both substantia nigra and striatum in the 6-OHDA-injected group compared to the sham group when examined 5 weeks post injection. However, the 6-OHDA-mediated reduction in TH immunoreactivity was significantly alleviated by daily intraperitoneal injection of DP. b, c Quantitative analysis of TH+ cells in the SNpc (b) and TH density in the striatum (c). *P < 0.05, **P < 0.01, ANOVA. Data are expressed as mean ± SD, n = 5 in each group. Scale bar, 1 mm

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