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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Effectiveness and mechanisms of adipose-derived stem cell therapy in animal models of Parkinson’s disease: a systematic review and meta-analysis

Fig. 3

Effects of ADSCs intervention. a Effect of ADSC intervention on rotation behavior reported in 10 individual experiments. The pooled effect size of standard mean difference (SMD) for rotation improvement was − 2.24 (95% CI, − 3.12 to − 1.36, z-value = 3.85, P < 0.000 01). b Stratified meta-analysis of the effects of ADSC intervention on rotation behavior by the type of ADSCs (original ADSCs, pooled estimate − 2.18, 95% CI − 3.29 to − 1.07, P = 0.000 1; and neural induction form of ADSCs, pooled estimate − 2.59, 95% CI − 3.57 to − 1.61, P < 0.000 01). c Effect of ADSC intervention on rotarod test reported in 3 individual experiments. The pooled effect size of SMD was 1.75 (95% CI, 0.80 to 2.71, z-value = 3.60, P = 0.000 3)

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