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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Pharmacological inhibition of asparaginyl endopeptidase by δ-secretase inhibitor 11 mitigates Alzheimer’s disease-related pathologies in a senescence-accelerated mouse model

Fig. 1

Protein expression and activity of AEP in brains of SAMP8 and SAMR1 mice. a Western blotting bands of mature AEP in the hippocampus and cortex of 4-month-old SAMP8 mice and age-matched SAMR1 mice. b Activity of AEP in the whole brains of 4-month-old SAMP8 and SAMR1 mice. * P < 0.05, Student’s t-test, n = 5 per group. c Mature AEP in the hippocampus and cortex of 6-month-old SAMP8 mice and age-matched SAMR1 mice. d AEP activity in the whole brains of 6-month-old SAMP8 and SAMR1 mice. * P < 0.05, unpaired Student’s t-test, n = 5 per group

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