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Fig. 5 | Translational Neurodegeneration

Fig. 5

From: Race modifies default mode connectivity in Alzheimer’s disease

Fig. 5

Connectivity and biomarker relationships in African Americans for which interaction term regression coefficient (race X biomarker) is significantly different from zero. Figure depicts regression relationship between connectivity and biomarkers in African Americans. Red line indicates connectivity increases as disease burden for that biomarker increases (see indication for each biomarker). Blue line indicates connectivity significantly decreases as disease burden for that biomarker increases (see indication for each biomarker). Gray outline indicates no significant relationship for African Americans between connectivity and biomarker. Dashed line indicate CSF tau, solid line indicates cognitive performance, and dotted line indicates CSF amyloid. * = indicates for that relationship, NHWs had significantly stronger (more negative) relationship than AAs. TP = temporal pole, vlTC = ventro-lateral temporal cortex, dmPFC = dorsomedial prefrontal cortex, dlTC = dorso-lateral temporal cortex, TPJ = temporal parietal junction, pIPL = posterior inferior parietal lobule, pHG = parrahippocampal gyrus, vmPFC = ventro-medial prefrontal cortex, PCC = posterior cingulate cortex

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