| | All participants | CN | MCI |
|---|
β coefficient | P value | β coefficient | P value | β coefficient | P value |
|---|
CSF t-tau | 0.56 | < 0.001 | 0.38 | < 0.001 | 0.67 | < 0.001 |
CSF p-tau | 0.35 | < 0.001 | 0.27 | < 0.001 | 0.40 | < 0.001 |
CSF Aβ42 | −0.02 | 0.97 | −0.01 | 0.82 | −0.07 | 0.69 |
- Aβ β-amyloid, CABLE Chinese Alzheimer’s Biomarker and Lifestyle, CN Cognitively normal, CSF Cerebrospinal fluid, MCI Mild cognitive impairment, p-tau Phosphorylated tau, t-tau Total tau.
- aData are β coefficients (with P values) from linear regression models for correlations between CSF α-synuclein and other biomarkers, adjusted for age, gender, educational level and APOE ε4 genotype. Models were tested in the whole cohort and in individual diagnostic groups
