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Table 1 Demographics of the study population in CABLE a

From: Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders

 

CN (n = 457)

MCI (n = 194)

P value

AGE, mean (SD), years

60.93 (10.55)

65.44 (10.01)

< 0.001

Female, n (%)

269 (58.9)

109 (56.2)

0.59

APOE ε4 genotype carriers, n (%)

69 (15.1)

35 (18.0)

0.41

Education, mean (SD), years

10.38 (6.12)

8.56 (4.23)

< 0.001

CSF α-synuclein, mean (SD), ng/l

1466.73 (813.99)

1501.19 (914.13)

0.61

CSF p-tau, mean (SD), ng/l

38.11 (9.69)

40.04 (12.42)

0.03

CSF t-tau, mean (SD), ng/l

173.3 (77.96)

191.02 (122.57)

0.03

CSF Aβ42, mean (SD), ng/l

160.01 (91.51)

162.10 (105.53)

0.81

  1. β-amyloid, CN Cognitively normal, CSF Cerebrospinal fluid, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, p-tau Phosphorylated tau, t-tau Total tau.
  2. aP values from the Kruskal-Wallis test or Fisher exact test