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Table 1 Demographics of the study population in CABLE a

From: Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders

  CN (n = 457) MCI (n = 194) P value
AGE, mean (SD), years 60.93 (10.55) 65.44 (10.01) < 0.001
Female, n (%) 269 (58.9) 109 (56.2) 0.59
APOE ε4 genotype carriers, n (%) 69 (15.1) 35 (18.0) 0.41
Education, mean (SD), years 10.38 (6.12) 8.56 (4.23) < 0.001
CSF α-synuclein, mean (SD), ng/l 1466.73 (813.99) 1501.19 (914.13) 0.61
CSF p-tau, mean (SD), ng/l 38.11 (9.69) 40.04 (12.42) 0.03
CSF t-tau, mean (SD), ng/l 173.3 (77.96) 191.02 (122.57) 0.03
CSF Aβ42, mean (SD), ng/l 160.01 (91.51) 162.10 (105.53) 0.81
  1. Aβ β-amyloid, CN Cognitively normal, CSF Cerebrospinal fluid, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, p-tau Phosphorylated tau, t-tau Total tau.
  2. aP values from the Kruskal-Wallis test or Fisher exact test
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Translational Neurodegeneration

ISSN: 2047-9158

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