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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders

Fig. 2

Associations between CSF α-synuclein and longitudinal neuroimaging change in ADNI. Data from linear mixed-effects models (left) and cox proportional hazards models (right) were adjusted for age, gender, educational level and APOE ε4 genotype. Hippocampal volume on the y axis was log-transformed to ensure normality. Time (years) on the x axis indicated follow-up years, in which “0” indicating the baseline. All participants were classified into High and Low groups according to their baseline CSF α-synuclein concentration (High: greater than median; Low: less than median)

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