Fig. 1

Scatter plots of cerebrospinal fluid α-synuclein concentrations in the diagnostic groups. The colors of the scatterplots are grouped by different diagnostic groups. The three horizontal black lines in each boxplot indicate the median and interquartile range. The whiskers extend to the minimum and maximum CSF α-synuclein data points. a CSF α-synuclein concentration in the diagnostic groups. b CSF α-synuclein concentration in the diagnostic groups stratified by Aβ pathology. c CSF α-synuclein concentration in the AD pathophysiology (tau and amyloid-β) positive and negative subgroups. A-, Aβ negative; A+, Aβ positive; T-, tau negative; T+, tau positive