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Fig. 7 | Translational Neurodegeneration

Fig. 7

From: Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance

Fig. 7

Effect of single or combined treatment with Anle 138b and PD03 on IgG binding in the brain and on the plasma antibody titers in PLP-α-syn mice. a IgG binding analysis. *P < 0.05; **P < 0.01, one-way ANOVA with post-hoc Tukey’s test. b Kinetics of plasma titers of anti-α-syn antibodies. Area under ROC curve analysis (*P = 0.0433). c Kinetics of plasma titers of anti-KLH antibodies. Area under ROC curve analysis (P = 0.2482)

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