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Fig. 4 | Translational Neurodegeneration

Fig. 4

From: SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer’s disease

Fig. 4

Brain distribution of [125I]RmAb158-scFv8D3 (a) and [125I]RmAb158 (b) in tg-ArcSwe mice, as revealed by Aβ40 immunohistochemical staining, ex vivo autoradiography 6 days post injection, and a merge of nuclear track emulsion (NTE) autoradiography (white puncta) in combination with Aβ immunofluorescence (red) 3 days post injection

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