Fig. 1From: SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer’s diseaseRepresentative normalized LigandTracer sensograms of (a) [125I]RmAb158-scFv8D3 (blue) and [125I]RmAb158 (red) binding to Aβ protofibrils, and of (b) [125I]RmAb158-scFv8D3 binding to mTfR. The dots represent raw data and solid lines represent curve fit using a 1:1 model with depletion correctionBack to article page