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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson’s disease

Fig. 3

1,25(OH)2D3 also exerts neuroprotective effects through genomic and/or non-genomic activation. ARE, antioxidant response element; GFR α1, GDNF family receptor alpha 1; γ-GT, gamma-glutamyl transferase; GSH, glutathione; GSNOH, S-nitrosoglutathione; RXR, retinoid X receptor; ROS, reactive oxygen species; PMCA, plasma membrane Ca2+ ATP-ase; Nrf2, nuclear factor erythroid 2-related factor 2; VDR, vitamin D receptor; VDREs, vitamin D response elements. The arrows indicate signaling components that are either enhanced (red arrows) or reduced (green arrows)

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Translational Neurodegeneration

ISSN: 2047-9158

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