Fig. 1
From: Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease
RIN3 is upregulated in APP/PS1 mice hippocampus at 3 months. a: RIN3 mRNA was measured in cerebellum, cortex, hippocampus, olfactory bulb of APP/PS1 and WT at different ages as indicated (n = 3 for all age groups). Hippocampus (b), cortex (c) and olfactory bulb (d) were further examined in great details. Data are mean ± SEM, p < 0.05 (*), p < 0.001 (***), n.s: non-significant, two-way ANOVA; e. RIN3 protein levels were measured by SDS-PAGE immunoblotting with a specific antibody against RIN3, with tubulin as a loading control. The intensity of RIN3 bands was quantitated using BioRad-ImageLab. P < 0.05 (*), standard t-test