Table 1 Demographic and neuropsychological data

Age (years)

73.23 ± 6.69

71.28 ± 5.45

1.82

0.07^b

Education (years)

16.56 ± 2.09

16.91 ± 2.13

−0.94

0.35^b

Gender (male/female)

24/40

24/42

0.02

0.89^a

APOE phenotypes (+/+, +/−, −/−)

62/64 (2/13/47)

58/66 (3/23/32)

5.70

0.06^a

CSF Aβ_1–42 (pg/mL)

25/64 (1401.04 ± 441.21)

11/66 (1284.44 ± 272.65)

0.81

0.43^b

CSF t-tau (pg/mL)

25/64 (255.99 ± 129.08)

11/66 (185.44 ± 45.89)

1.75

0.09^b

CSF p-tau (pg/mL)

25/64 (23.56 ± 14.02)

11/66 (16.19 ± 4.19)

1.70

0.10^b

[¹⁸F] AV45 SUVRs

40/64 (1.11 ± 0.18)

34/66 (1.15 ± 0.18)

−0.91

0.37^b

Intracranial volume (cm³)

1390.55 ± 175.92

1407.89 ± 132.81

−0.64

0.53^b

 Gray matter volume (cm3)

593.04 ± 61.13

604.97 ± 44.95

−1.27

0.21^b

 White matter volume (cm3)

511.48 ± 83.31

514.20 ± 63.25

−0.21

0.83^b

 Ventricular volume (cm3)

286.03 ± 55.57

288.73 ± 52.68

−0.28

0.78^b

Hippocampal volume (cm3)

8.93 ± 0.99

8.95 ± 0.88

−0.13

0.90^b

 Left hippocampal volume (cm3)

4.45 ± 0.50

4.48 ± 0.48

−0.36

0.72^b

 Right hippocampal volume (cm3)

4.48 ± 0.52

4.47 ± 0.43

0.12

0.91^b

GDS-15

0 (0–1)

1 (0–1)

−1.86

0.06^c

NPI

0 (0–1)

0 (0–0.25)

−0.78

0.44^c

CCI

–

20 (17.75–26)

–

–

MMSE

28.88 ± 1.53

29.02 ± 1.14

−0.59

0.55^b

LM-immediate

15.28 ± 3.60

14.65 ± 3.20

1.01

0.29^b

LM-delayed recall

11.31 ± 1.55

11.14 ± 1.58

0.64

0.52^b

RAVLT-total

48.64 ± 9.64

46.42 ± 9.52

1.32

0.19^b

RAVLT-delayed recall

6.31 ± 2.19

6.39 ± 2.26

−0.21

0.84^b