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Table 1 Table summarizing key findings from stool microbiome studies in PD patients compared to healthy controls

From: Microbiome changes: an indicator of Parkinson’s disease?

  Qian et al. [42]Lin et al. [43]Bedarf et al. [44]Petrov et al. [45]Keshavarzian et al. [39]Scheperjans et al. [46]Hopfner et al. [47]Hasegawa et al. [48]Li et al. [49]Hill-Burns et al. [50]Unger et al. [51]Heintz- Buschart et al. [40]Li, F et al. [52]Pietrucci et al. [53]Lin, A et al. [54]
Alpha diversity +*+*=-*+*== =    ==
Beta diversity *******  *  ***
FamilyGenus               
Enterobacteriaceae   - +  + +*  +* 
Pasteurellaceae   -     --*  +* -*
Bifidobacteriaceae   - - + ++*    +*
 Bifidobacterium  -+*-  = +*+*    
Bacteroidaceae   - +* + --*     
 Bacteroides  --*+*    -*  -*  
Porphyromonadaceae  +*- +   -+*  +*  
Prevotellaceae  -*-* =-*- = -*-   
 Prevotella -*-*-*=  -   --*  
Rikenellaceae +*+*+ +   -      
Lactobacillaceae -*+*-  +*+* ++*   +* 
 Lactobacillus-*+*-+*   +* +*-*    
EnterococcaceaeEnterococcus +*-    ++* -*    
Lachnospiraceae   -* -*   --*  +*-*-*
Ruminococcaceae   - ++- -   +*  
 Faecalibacterium -*--*-   -*-*-*    
Erysipelotrichaceae +*+*-* -   =  +   
Verrucomicrobiaceae  +*+* +*+*+ =+* +*+*  
AkkermansiaceaeAkkermansia +*+* +*    +*++*+*  
  1. + = higher in PD patients compared to controls; - = higher in controls compared to PD patients; * = p < 0.05