Translational Neurodegeneration

Table 1 Table summarizing key findings from stool microbiome studies in PD patients compared to healthy controls

From: Microbiome changes: an indicator of Parkinson’s disease?

		Qian et al. [42]	Lin et al. [43]	Bedarf et al. [44]	Petrov et al. [45]	Keshavarzian et al. [39]	Scheperjans et al. [46]	Hopfner et al. [47]	Hasegawa et al. [48]	Li et al. [49]	Hill-Burns et al. [50]	Unger et al. [51]	Heintz- Buschart et al. [40]	Li, F et al. [52]	Pietrucci et al. [53]	Lin, A et al. [54]
Alpha diversity		+*	+*	=	-*	+*	=	=		=					=	=
Beta diversity		*	*	*	*	*	*	*			*			*	*	*
Family	Genus
Enterobacteriaceae				-		+			≈	+		+*			+*
Pasteurellaceae				-						-	-*			+*		-*
Bifidobacteriaceae				-		-		+		+	+*					+*
	Bifidobacterium			-	+*	-			=		+*	+*
Bacteroidaceae				-		+*		+		-	-*
	Bacteroides			-	-*	+*					-*			-*
Porphyromonadaceae			+*	-		+				-	+*			+*
Prevotellaceae			-*	-*		=	-*	-		=		-*	-
	Prevotella		-*	-*	-*	=			-				-	-*
Rikenellaceae		+*	+*	+		+				-
Lactobacillaceae		-*	+*	-			+*	+*		+	+*				+*
	Lactobacillus	-*	+*	-	+*				+*		+*	-*
Enterococcaceae	Enterococcus		+*	-					+	+*		-*
Lachnospiraceae				-*		-*				-	-*			+*	-*	-*
Ruminococcaceae				-		+	+	-		-				+*
	Faecalibacterium		-*	-	-*	-				-*	-*	-*
Erysipelotrichaceae		+*	+*	-*		-				=			+
Verrucomicrobiaceae			+*	+*		+*	+*	+		=	+*		+*	+*
Akkermansiaceae	Akkermansia		+*	+*		+*					+*	+	+*	+*

+ = higher in PD patients compared to controls; - = higher in controls compared to PD patients; * = p < 0.05

Back to article page

ISSN: 2047-9158

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com