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Table 1 Demographic, neuropsychological, blood, and cerebral markers of the study sample

From: Lower serum expression of miR-181c-5p is associated with increased plasma levels of amyloid-beta 1–40 and cerebral vulnerability in normal aging

 

Sample (N = 95)

Age

68.8 ± 4 (62–78)

Sex (M/W)

54/41

ApoE ε4 (yes/no)

21/74

CDR

0

MMSE

29.3 ± 1.2 (26–30)

MFQ

36.8 ± 10.5 (16–66)

FCSRT

13.7 ± 2 (8–16)

TOL

413 ± 139 (132–824)

Boston naming test

52.3 ± 4.5 (40–59)

miR-181c-5p (fold change)

0.66 ± 0.37 (0.07–1.5)

1–40 (pg/ml)

228.8 ± 32.6 (167.7–316)

1–42 (pg/ml)

24 ± 7.4 (7.6–59)

L hippocampus (mm3)

3140 ± 328 (2450–4043)

R hippocampus (mm3)

3242 ± 330 (2487–4080)

L entorhinal (mm3)

1144 ± 124 (862–1499)

R entorhinal (mm3)

1670 ± 199 (1131–2162)

L parahippocampal (mm3)

3355 ± 635 (2046–5411)

R parahippocampal (mm3)

3154 ± 539 (2090–4488)

  1. Results are expressed as mean ± standard deviation for each group, range (min-max)
  2. M Men, W Women, CDR Clinical dementia rating, MMSE Mini mental state examination, MFQ Memory functioning questionnaire, FCSRT Free and cued selective reminding test, TOL Tower of London, L Left and R Right