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Fig. 6 | Translational Neurodegeneration

Fig. 6

From: Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model

Fig. 6

GFAP (astrocytes) area covered decreases on APP/PS1 mice treated with BM-M. a, b Representative GFAP immunostaining comparison between PBS injected mice (control) and BM-M treated mice showing less area covered by GFAP in the brains of the transplanted mice group. c Percentage of GFAP+ area covered in cortex, hippocampus and brainstem individually, shows a significant decrease in the brain stem area of BM-M treated mice. Bar graphs display the mean ± SEM (error bars) (*p < 0.05). d Percentage of GFAP+ area covered in total brain area shows a significant reduction upon BM-M transplantation

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