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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model

Fig. 3

[37-42] plaques number decrease in cortex and hippocampus of APP/PS1 mice treated with BM-M. a, b Representative Aβ[37-42] plaques immunostaining comparison between PBS injected mice (control) and BM-M treated mice, showing less large plaques in transplanted animals. c-e Small, medium and large plaque number per mm2 in cortex, hippocampus and brainstem comparison between control and BM-M treated mice showing a reduction of larger plaque in cortex and hippocampus. f-h Representative images of different plaque sizes stained by immunohistochemistry are shown. Bar graphs display the mean ± SEM (error bars) of plaque (*p < 0.05)

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