Fig. 2

Average size of Aβ[37-42] plaques in cortex, hippocampus and brainstem. BM-M transplantation decreases Aβ plaques size in the hippocampus of the APP/PS1 treated mice (n = 6) compared to control group (n = 6) (a-c). Representative co-staining of Aβ_[37-42] (purple) and Aβ-pE3 plaques (orange), showing the dense Aβ-pE3 plaque modification localized in the centre of a Aβ_[37-42] plaque (d-f). Bar graphs display the mean ± SEM (error bars) of plaque and student’s t-test was used for statistical analysis (*p < 0.05)