Table 2 Age-associated retinal structural changes in APP/PS1 and WT mice*
Time-point (months) | Inner retina | Outer retina |
|---|---|---|
APP/PS1 | ||
3 | 31.2 ± 0.8b,d | 54.7 ± 1.4a,b |
6 | 30 ± 1.1b | 53 ± 1.9 |
9 | 29 ± 1b | 52.1 ± 2a |
12 | 28.5 ± 0.7d,b | 51 ± 2.3b |
p-value (ANOVA) | < 0.0001 | < 0.01 |
WT | ||
3 | 31.3 ± 0.7a,b | 54.1 ± 1 |
6 | 30.5 ± 0.9 | 53.9 ± 1.7 |
9 | 30.4 ± 0.7a | 53.5 ± 1.5 |
12 | 30.1 ± 0.9b | 53.1 ± 1 |
p-value (ANOVA) | < 0.01 | 0.1 |