Fig. 5From: A longitudinal assessment of retinal function and structure in the APP/PS1 transgenic mouse model of Alzheimer’s diseaseAβ distribution in the hippocampus and retina of the APP/PS1 mice at 3,6,12 months of age (Dentate Gyrus, CA1-CA3 regions of the hippocampus and retinal layers are shown)- Scale bar for hippocampus and retina is 100 μm and 20 μm, respectively. An increase in Aβ levels in both regions were observed. Retinal Aβ was observed in the inner/outer retinal regions from 6 months and was more pronounced in the GCL by 12 months of age. (Images for WT in Additional file 1: Figure S1)Back to article page