Skip to main content

Table 3 Neurodegenerative processes-related genes among the target output from the differentially expressed miRNAs

From: Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer’s disease and dementia with Lewy bodies

Input Gene Input miRNA Start Stop Computational Predictions Confirmed Predictions
ADAM10 hsa-let-7i-5p 783 801 Miranda 0
hsa-miR-23a-3p 1477 1499 Miranda 0
hsa-miR-451a 3640 3660 Miranda 0
AKT1 hsa-miR-451a 60 79 Miranda Mirtarbase
APP hsa-let-7i-5p 532 553 Miranda 0
APPBP2 hsa-let-7i-5p 3533 3553 Miranda 0
hsa-miR-151a-3p 1868 1888 Miranda 0
hsa-miR-21-5p 4099 4120 Miranda 0
BCL2 hsa-miR-126-3p 4169 4192 Miranda 0
hsa-miR-23a-3p 4400 4418 Miranda 0
CASP2 hsa-let-7i-5p 2265 2285 Miranda 0
hsa-miR-151a-3p 2025 2045 Miranda 0
CASP3 hsa-let-7i-5p 141 160 Miranda 0
hsa-miR-23a-3p 808 828 Miranda 0
CASP8 hsa-miR-21-5p 867 888 Miranda 0
hsa-let-7i-5p 118 139 Miranda 0
CASP10 hsa-miR-23a-3p 2104 2124 Miranda 0
CASP14 hsa-let-7i-5p 56 77 Miranda 0
CCNE2 hsa-miR-126-3p 1212 1233 Miranda Mirtarbase
hsa-miR-151a-3p 249 270 Miranda 0
hsa-let-7i-5p 350 370 Miranda 0
COX6B2 hsa-let-7i-5p 69 91 Miranda 0
COX6C hsa-miR-21-5p 312 332 Miranda 0
COX7A1 hsa-let-7i-5p 49 54 Rnahybrid 0
COX7B hsa-let-7i-5p 301 321 Miranda 0
hsa-miR-23a-3p 832 852 Miranda 0
COX11 hsa-miR-151a-3p 1584 1604 Miranda 0
GSK3B hsa-miR-21-5p 912 934 Miranda 0
hsa-let-7i-5p 320 342 Miranda 0
hsa-miR-21-5p 5125 5147 Miranda 0
hsa-miR-23a-3p 988 1008 Miranda 0
MIF hsa-miR-451a 90 109 Miranda Mirtarbase|OncomiRDB|
UBE2J1 hsa-miR-23a-3p 1920 1942 Miranda 0
UBE2G2 hsa-let-7i-5p 251 272 Miranda 0
UBE2L3 hsa-miR-451a 322 343 Miranda 0
hsa-miR-23a-3p 1188 1209 Miranda 0
  1. MirGate results for Computational and (when possible) Confirmed target genes are shown (in alphabetical order). The name of the prediction tool reporting each target gene is indicated. “0” means no confirmation was found in the analysis for that specific target. Start and Stop indicate the miRNA binding site (beginning and ending nucleotide) in the targeted gene sequence. Key: ADAM10 ADAM Metallopeptidase Domain 10), APP, β-amyloid precursor), APPBP2 Amyloid protein-binding protein 2, GSK3B Glycogen synthase kinase 3, AKT1 RAC-alpha serine/ threonine-protein kinase, CAB39 Calcium binding protein 39, CASP Caspase, CCNE Cyclin E, COX Cytochrome c oxidase, MIF Macrophage migration inhibitory factor, UBE2 Ubiquitin Conjugating enzyme E2