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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Alzheimer’s in a dish – induced pluripotent stem cell-based disease modeling

Fig. 2

Reprogramming of human fibroblasts (hFib) to iPSCs. a Human skin biopsy-derived fibroblasts in culture. [1] hFib growing out of the biopsy (black). [2] Phase contrast image of isolated hFib. [3] hFib stained with Alexa Fluor 488 Phalloidin. b IPSC colonies after reprogramming. [1] Light microscopic image of a single iPSC colony. [2–6] Immunostained iPSC colonies showing expression of typical pluripotency marker proteins. [2] DAPI, [3] Oct4, [4] Tra-1-60, [5] Nanog, [6] merged images

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