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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Current progress of mitochondrial transplantation that promotes neuronal regeneration

Fig. 1

Injury-induced morphogenesis and distribution of mitochondria in neurons. a Healthy neurons. b (upper panel) In response to neuronal injury, the size and number of mitochondria are increased around the axon hillock. (bottom panel) Stimuli, such as low-dose ionizing radiation stress, induces mitochondrial fusion [56]. c During neuronal regeneration, density of mitochondria and their transport are increased in the regenerating axon. Moreover, knockout of Snph or overexpressing Armcx1 have been shown to improve mitochondrial motility and promote axonal regeneration [59, 60]

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