Table 5 Apolipoprotein E-adjusted estimates of the association of 5-hydroxytriptamine transporter gene-linked polymorphic region (5-HTTLPR) S-plus carriers with neuropsychiatric symptoms in patients with Alzheimer’s disease (AD) according to to the presence of delusion symptom

Hallucination

(0.412–1.700)

(0.529–3.900)

–

–

–

Agitation/aggression

(0.314–1.770)

(0.769–6.770)

0.160

1.586

(0.833–3.020)

Depressed mood

(0.236–2.240)

(0.178–2.540)

0.611

1.960

(1.480 × 10⁻¹ - 2.610 × 10¹)

Anxiety

(0.166–1.500)

(0.174–2.670)

0.610

1.730

(2.110 × 10⁻¹ - 1.427 × 10¹)

Euphoria

(0.631–1.560)

(0.628–2.330)

–

–

–

Apathy

(0.306–3.440)

(0.306–5.270)

0.690

1.780

(1.070 × 10⁻¹ - 2.950 × 10¹)

Disinhibition

(0.990–1.020)

(0.987–1.030)

–

–

–

Irritability/liability

(0.344–2.510)

(0.988–12.500)

0.280

1.505

(0.720–3.150)

Aberrant motor activity

(1.004–2.850)

(1.195–4.260)

0.550

1.407

(0.461–4.300)

Sleep disturbances

(0.299–2.850)

(0.330–4.860)

0.923

1.130

(8.860 × 10⁻² - 1.450 × 10¹)

Eating disorder

(0.521–4.180)

(0.364–3.710)

0.514

2.380

(1.780 × 10⁻¹ - 3.186 × 10¹)