Table 3 Genetic characteristics of patients with Alzheimer’s disease (AD) according to the presence of delusion symptom

5-HTTLPR L/S

64

(37.43%)

53

(61.63%)

0.000

0.226

(0.111–0.459)

117

(45.53%)

5-HTTLPR S/S

27

(15.79%)

18

(20.93%)

0.003

0.281

(0.115–0.682)

45

(17.51%)

HWE

5-HTTLPR L

224

(0.655)

83

(0.483)

307

(0.597)

5-HTTLPR S

118

(0.345)

89

(0.517)

0.000

0.491

(0.332–0.726)

207

(0.403)

APOE ε2/ε2

–

–

–

–

–

–

–

–

–

APOE ε2/ε3

8

(4.68%)

7

(8.14%)

0.243

0.486

(0.150–1.586)

15

(5.84%)

APOE ε2/ε4

3

(1.75%)

5

(5.81%)

0.110

0.255

(0.046–1.286)

8

(3.11%)

APOE ε3/ε3

120

(70.18%)

51

(59.30%)

171

(66.54%)

APOE ε3/ε4

39

(22.81%)

21

(24.42%)

0.518

0.789

(0.405–1.544)

60

(23.35%)

APOE ε4/ε4

1

(0.58%)

2

(2.33%)

0.220

0.213

(0.007–3.081)

3

(1.17%)

HWE

APOE ε2

11

(0.032)

12

(0.070)

0.041

0.415

(0.166–1.038)

23

(0.045)

APOE ε3

287

(0.839)

130

(0.756)

417

(0.811)

APOE ε4

44

(0.129)

30

(0.174)

0.138

0.664

(0.388–1.139)

74

(0.144)