Fig. 3

Gene Ontology (GO) biological process (BP) terms associated with GM6-increased genes. (a – d) Top-ranked GO BP terms. Figures list GO BP terms most strongly enriched with respect to the GM6-increased DEGs (FDR < 0.10, FC > 1.50) identified at (a) 6 h, (b) 24 h, (c) 48 h and (d) 6–48 h. The number of GM6-increased genes associated with each GO BP term is listed in parentheses (left margin) and exemplar genes for each term are listed in each figure. Statistical significance of enrichment (horizontal axis) was evaluated using a hypergeometric test. Labels associated with some GO BP terms are abbreviated. (e – i) Heatmaps show GM6-increased genes associated with (e) generation of neurons (GO:0048699), (f) signaling (GO:0023052), (g) regulation of multicellular organismal development (GO:2000026), (h) regulation of cell adhesion (GO:0030155) and (i) wound healing (GO:0042060). The genes shown for each GO BP term were most strongly increased by GM6 at (e – g) 6 h, (h) 24 h or (i) 48 h