From: Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
Treatment | Genotyping | n | Gender (m/f) | Weight (AVG ± SD) | Pde6b | Experimental Use (n) | |||
---|---|---|---|---|---|---|---|---|---|
Behavioral Tests | WB | IF | Q-PCR | ||||||
Vehicle | Eu | 10 | 6/4 | 31.5 ± 7.2 | 0 | 10 | 8 | 4 | 6 |
Ts65Dn | 10 | 5/5 | 25.7 ± 3.2 | 0 | 10 | 8 | 4 | 6 | |
InRapa | Eu | 10 | 6/4 | 31.8 ± 6.8 | 0 | 10 | 8 | 4 | 6 |
Ts65Dn | 10 | 6/4 | 28.9 ± 5.6 | 0 | 10 | 8 | 4 | 6 |