Fig. 1
From: Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
Schematic of InRapa treatment. 6-month old Ts65Dn mice and euploid (Eu) were administered with intranasal rapamycin (InRapa; Rapamune, Pfizer) 1 μg/mouse and Vehicle (Veh; saline with 1% DMSO) for 90 days total. At day 77 cognitive tests (NOR and RAM) has been initiated while at day 90 mice has been sacrificed to perform PCR, IHC and WB on collected brain samples