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Table 1 The demographic, cognitive and neuropathological information

From: Aberrant functional connectivity network in subjective memory complaint individuals relates to pathological biomarkers

Variables NC SMC T/χ2- value P value
Number 40 44   
Demographic characteristics
 Age, y, mean (SD) 75.10±5.39 73.78±5.81 1.08 0.28
 Female, n (%) 22/18 24/20 0.002 0.57
 Education (y), mean (SD) 16.70±2.39 16.66±2.60 0.08 0.94
 Family, yes/no 23/17 14/30 7.28 0.03*
 APOE 27/13 35/9 1.57 0.16
CSF
 Aβ1–42 (pg/ml) 1389.89±755.77 1552.79±683.30 -0.75 0.46
 T-Tau (pg/ml) 235.32±83.46 259.52±68.76 -1.05 0.30
 P-Tau181 (pg/ml) 21.80±8.80 23.50±6.10 -0.73 0.47
Neuropsychiatric Scores
 CCI   31.37±8.30  
 GDS 0.68±0.89 1.14±0.90 -2.36 0.02*
General mental status
 MMSE 29.05±1.18 29.36±0.75 -1.44 0.15
Memory function
 WMS-LM immediate 15.00±2.67 15.25±3.01 -0.39 0.70
 WMS-LM delay 14.38±2.83 14.23±3.40 0.22 0.83
 AVLT sum of trials 1–5 44.95±9.43 48.84±9.59 -1.86 0.07
 AVLT30 7.18±4.14 8.88±4.18 -1.85 0.07
Attention
 Log-transformed TMT-A 1.50±0.12 1.48±0.14 0.59 0.55
Decision-making function
 Log-transformed TMT-B 1.79±0.16 1.84±0.17 -1.36 0.18
Language
 BNT total 28.94±1.05 28.52±1.50 1.14 0.26
 Category fluency 21.75±4.06 22.20±5.02 -0.45 0.65
Visuospatial processing
 CDT 4.85±0.36 4.86±0.35 -0.18 0.86
 Ecog PT: memory 1.53±0.41 1.94±0.60 -3.73 <0.001*
 Ecog PT: global 1.35±0.26 1.55±0.38 -2.85 0.006*
 Ecog Inf: memory 1.24±0.40 1.59±0.59 -3.18 0.002*
 Ecog Inf: global 1.22±0.34 1.43±0.52 -2.15 0.03*
  1. Data are presented as means ± standard deviations.
  2. Abbreviation: SMC Significant Memory Complaint, NC Normal Controls, GDS Geriatric Depression Scale, MMSE Mini-Mental State Examination, WMS-LM Wechsler Memory Scale Logical Memory, AVLT Auditory Verbal Learning Test, TMT Trail-Making Test, BNT Boston Naming Test, CDT Clock Drawing Test, E-Cog Measurement of Everyday Cognition, PT patient-based, Inf Informant-based;
  3. *p<0.05, significant difference between NC and SMC
  4. Notably: The CSF data in Table 1 only represents the subjects who had CSF sample.