CSF Aβ1–42 level is associated with cognitive decline in early Parkinson’s disease with rapid eye movement sleep behavior disorder

Table 2 Baseline specific cognitive characteristics of PD stratified by RBD

Cognitive domain	Measure	PD with RBD(N = 136)	PD without RBD(N = 214)	P value
Verbal memory	HVLT Total Recall	45.23 ± 10.80	47.69 ± 10.83	0.039*
	HVLT Recognition Discrimination	47.52 ± 13.05	49.70 ± 10.86	0.092
Visuospatial function	Benton Judgment of Line Orientation	12.65 ± 2.82	13.21 ± 2.58	0.058
Processing speed /attention	Symbol Digit Modalities	43.64 ± 9.08	46.36 ± 9.36	0.008*
Executive function /working memory	Letter-Number Sequencing	11.17 ± 2.53	11.72 ± 2.71	0.06
	Semantic Fluency total	50.19 ± 9.24	51.31 ± 10.40	0.305

Results are mean ± (SD). P value was assessed using two-tailed Student t test for each variable. *P value statistically significant. The PD with RBD group performed worse on the HVLT total recall and Symbol Digit Modalities
Abbreviations: PD Parkinsonr’s disease, RBD Rapid eye movement sleep behavioral disorder, HVLT Hopkins Verbal Learning Test

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