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Fig. 5 | Translational Neurodegeneration

Fig. 5

From: Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson’s disease

Fig. 5

AAV-hm-α-syn injected in the OB increased pSer129 α-syn in multiple brain regions. a Expression of hm-α-syn in the OB increased the level of pSer129 α-syn in multiple-brain regions. OB, olfactory bulb; AON, anterior olfactory nucleus; Piri: piriform cortex; PFC: prefrontal cortex; LS: lateral septal nucleus; CPU: caudate putamen; Hip: hippocampus; LG: lateral geniculate nucleus; VTA: ventral tegmental area; SN: substantia nigra. b Comparing a number of the pSer129 α-syn+ cells between the experimental and control animals. Error bars represent mean ± SD, n = 8. Statistical comparisons were performed using the student’s test, *p < 0.05. (Bar: 20um)

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