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Fig. 10 | Translational Neurodegeneration

Fig. 10

From: Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson’s disease

Fig. 10

Immunofluorescent double-labeled staining in the SN field. a-c double staining of SN field by LC3B (green) and TUNEL staining (red) in the control rats. d-f double staining of SN field by LC3B (green) and TUNEL staining (red) in the hm-α-synuclein rats. These data indicates that the apoptosis happen in some cells overexpressing the hm-α-synuclein. g-i double staining of SN field by ThS (green) and pSer129-α-synuclein staining (red) in the control rats. j-l double staining of SN field by ThS (green) and pSer129-α-synuclein staining (red) in the hm-α-synuclein rats. These data indicates that pSer129-α-synuclein signals reflected LB pathological changes. (Bar: 20um)

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