|
Characteristics
|
CN (n = 32)
|
sMCI (n = 24)
|
pMCI (n = 47)
|
AD (n = 18)
|
|---|
|
Aβ42, pg/ml [mean (SE)]
|
226.1 (9.3) b, c, d
|
178.5 (10.9)a, c, d
|
147.5 (7.0)a, b
|
136.1 (6.4)a, b
|
|
T-tau, pg/ml [mean (SE)]
|
64.3 (3.7)c, d
|
87.2 (10.8)d
|
107.8 (7.2)a, d
|
153.2 (19.1)a, b, c
|
|
P-tau-181, pg/ml [mean (SE)]
|
22.2 (1.6)c, d
|
28.9 (3.1)c, d
|
39.5 (2.4)a, b
|
45.8 (3.9)a, b
|
|
VILIP-1, pg/ml [mean (SE)]
|
133.0 (6.7)c, d
|
146.0 (10.6)c, d
|
184.3 (9.4)a, b
|
189.7 (16.6)a, b
|
|
YKL-40, ng/ml [mean (SE)]
|
397.2 (25.7)
|
384.0 (28.1)
|
400.7 (19.4)
|
471.9 (39.5)
|
- P values indicate the values assessed with analyses of variance for each variable. Post hoc analysis provided significant differences between groups: afrom CN; bfrom sMCI; cfrom pMCI; dfrom AD
- Abbreviations: SE Standard error, VILIP-1 Visinin-like protein-1, YKL-40 Chitinase-3-like protein 1, CN cognitively normal, sMCI stable mild cognitive impairment, pMCI progressive mild cognitive impairment, AD Alzheimer’s disease
